Density-dependent growth inhibiting interactions between 3T3 and SV40-3T3 cells in mixed cultures.
نویسندگان
چکیده
3T3 cells are shown to reduce SV40-3T3 cell population growth in a denisty-dependent manner in co-cultures of 3T3 and SV40-3T3 cells. The development of this inhibitory activity roughly parallels the development of density-dependent inhibition of growth in homogeneous 3T3 control cultures. The extent of reduction of SV40-3T3 growth can be manipulated by pretreatment of 3T3 cells with a high serum concentration. SV40-3T3 growth rates are reduced by factors between 10 and 20 under optimum inhibitory conditions as compared to SV40-3T3 growth in control cultures.
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عنوان ژورنال:
- Zeitschrift fur Naturforschung. Section C, Biosciences
دوره 34 3-4 شماره
صفحات -
تاریخ انتشار 1979